Spirit is an animation tool for live-editing animations directly on a real webpage in the browser, pairing a desktop editor (Spirit Studio) with a Chrome extension rather than working in an isolated canvas.
Because you're animating the actual page rather than a mockup of it, what you see while designing is exactly what ships, the output is JSON animation data you copy straight into the site's code, aimed squarely at teams shipping directly to the web.
Designers working closely with developers to animate a real, already-built webpage; not the right tool for designing an animation before the page exists, which is where Fable or Jitter fit better.
A free-forever plan is available; paid licenses run around $10-12/month. Requires installing a desktop app and browser extension rather than working entirely in a browser tab.
The ultimate tool to create high-quality animations directly in the browser.